| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ca32fd2a44fd326ffd027a75a57bd13f |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2227-105
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2217-072
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2217-05
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2267-0393 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y302-01023
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-8509
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-90
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-2471 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-90
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-027
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 |
| filingDate |
2007-07-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5c617e76ad09c8563a2a146942b18801
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d9a723ff6081a6f039c46751f25a4fc7 |
| publicationDate |
2008-01-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
FR-2903118-A1 |
| titleOfInvention |
A METHOD FOR SPECIFIC REPLACEMENT OF A COPY OF A GENE PRESENT IN THE RECEIVER GENOME BY INTEGRATING A GENE DIFFERENT FROM THAT OR INTEGRATION |
| abstract |
The invention relates to the targeted insertion of a foreign DNA to a selected site in the genome of a eukaryotic cell. The chosen insertion site is in a gene. The targeted insertion is performed by transfecting eukaryotic cells with a vector containing the foreign DNA to be inserted flanked by two sequences that are respectively homologous to two genomic sequences that are adjacent to the desired insertion site in the recipient gene. insertion may comprise either a coding sequence or a regulatory sequence. The flanking sequences are chosen so as to allow, by homologous recombination, as the case may be, the expression of the coding sequence of the insertion DNA under the control of the regulatory sequences of the recipient gene, or the expression of a coding sequence. of the recipient gene under the regulatory sequence control of the insertion DNA. |
| priorityDate |
2007-07-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |