abstract |
Inhibitors of HPV of formula (I): where G1 represents a bond or a hydrocarbon chain optionally substituted with one or two alkyl groups, G2 represents a group in which: R represents a hydrogen, an alkyl, haloalkyl, or a pro-drug radical such carbamate, acetyl or dialkylaminomethyl, G represents a bond or a hydrocarbon chain optionally substituted by one or two alkyl, W represents an oxygen, a sulfur or NH, R1 and R2, each represent a group chosen from a hydrogen, a halogen, a hydroxyl, thio, alkoxy, haloalkoxy, alkylthio, haloalkylthio, amino, monoalkylainino, dialkylamino, cycloalkyl, alkyl or haloalkyl, R3 represents an acid or a pro-drug radical of the acid function or a bioisostere of the acid function, A represents a aryl, cycloalkyl, cycloalkenyl or a heterocycle, each optionally substituted, and B represents an aryl or a 6-membered heterocycle each optionally substituted, as well as their pharmaceutically acceptable salts. |