abstract |
The invention relates to a process for the preparation of ioxilan of the formula 5- (N-2,3-dihydroxypropylacetamido) -2,4,6-triiodo-N- (2,3-dihydroxypropyl) -N '- (2-hydroxyethyl) isophthalamide , by atomization, and the improved product thus obtained. This process avoids a crystallization process and leads to an active ingredient having improved solubility. |