| abstract |
The subject of the present invention is compounds corresponding to formula (I): in which: X represents an oxygen atom or a group = NO-R6; R1 represents a group chosen from -N (R7) SO2R8; N (R7) SO2NR9R10, -SR8, -SOR8, -SO2R8, -SO2NR9R10; R2 represents a hydrogen atom or a (C1-C4) alkyl; R3 represents: a (C1-C6) alkyl unsubstituted or substituted with: a) one or more halogen atoms, b) a non-aromatic (C3-C12) unsaturated or unsaturated carbocyclic ring, or (c) a non-substituted phenyl substituted or substituted d) unsubstituted or substituted naphthyl; a saturated or unsaturated, unsubstituted or substituted (C3-C12) non-aromatic carbocycle; a benzhydrylmethyl; R4 and R5 each independently represent a hydrogen atom, a halogen atom, a (C1-C4) alkyl, a (C1-C4) alkoxy, a trifluoromethyl radical, a preparation method and application in therapy. |