http://rdf.ncbi.nlm.nih.gov/pubchem/patent/FR-2892725-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_06ab2c9f6be7f0000339ad48dc1273c3 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2800-57 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-001 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61Q19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G69-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-88 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-27 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01P13-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08G69-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01P3-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61Q1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-88 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K17-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N25-10 |
| filingDate | 2005-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f9ed009fcb16c603fc4dcd989bfcc6df http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3038fd47d211ef37202f9f463c658053 |
| publicationDate | 2007-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | FR-2892725-A1 |
| titleOfInvention | POLYGLUTAMIC ACIDS FUNCTIONALIZED BY DERIVATIVES OF HISTIDINE AND HYDROPHOBIC GROUPS AND THEIR PARTICULARLY THERAPEUTIC APPLICATIONS |
| abstract | The present invention relates to novel materials based on modified, biodegradable polyamino acids, useful especially for the vectorization of active principle (s) (PA). The invention also relates to new pharmaceutical, cosmetic, dietetic or phytosanitary compositions based on these polyamino acids. The object of the invention is to provide a new polymer raw material, which can be used for the AP vectorization and making it possible to satisfy optimally to all the specifications required in this case: biocompatibility, biodegradability, ability to associate easily with many active ingredients or to solubilize them, and to release these active ingredients in vivo. This object is achieved by the present invention which concerns novel polyglutamates modified with histidine derivatives, and with hydrophobic groups containing from 8 to 30 carbon atoms. These polyglutamates modified with histidine derivatives are soluble at pH less than 5 and are able to be converted easily and economically into particles of vectorization of active ingredients, these particles themselves being able to form stable aqueous colloidal suspensions. These modified polyglutamates are however insoluble in water at physiological pH (7.4) and should therefore, during a subcutaneous injection, precipitate at the injection site. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/FR-2940619-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2010076519-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022194759-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8481019-B2 |
| priorityDate | 2005-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 220.