abstract |
wherein n represents the number 0 or 1; X represents a hydrogen or halogen atom; Y is OR3 or NR4R5; R1 represents a hydrogen atom or a (C1-C6) alkyl group; R2 represents a phenyl or a heteroaromatic group of the pyridinyl, pyrimidinyl, pyrazinyl or pyridazinyl type, the phenyl or the heteroaromatic group possibly carrying one or more halogen atoms and / or one or more (C1-C6) alkyl groups, (C1- C6) alkoxyl; R3 represents hydrogen, (C1-C6) alkyl or benzyl; and R4 and R6 each independently represent a hydrogen atom or a (C1-C6) alkyl group, or R2 and R3 together with the nitrogen atom aziridinyl, azetidinyl, pyrrolidinyl, piperidinyl, morpholinyl or piperazinyl, optionally substituted with (C1-C6) alkyl, phenyl, azetidinyl, in the form of a base or acid addition salt, as well as in the hydrate or solvate. Application in therapy. |