http://rdf.ncbi.nlm.nih.gov/pubchem/patent/FR-2879623-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_37f4922dfb7777b019e504b885211b8e http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e0bd2564785dbfbd379992a7ee616c6f |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6897 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-00 |
| filingDate | 2004-12-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f7dd4d97ededde2b9dd71ce7f86ed92a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_311ebd5fd625b1a1baf5c28175dce30a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_122664eaa13ae9a4b5dd0e9033a4290f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cb229d6d5081958d6a5a73704db0dc5f |
| publicationDate | 2006-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | FR-2879623-A1 |
| titleOfInvention | USE OF NUCLEOTIDE SEQUENCES INTERACTING PREFERENTIALLY WITH THE PPARALPHA TRANSCRIPTION COMPLEX |
| abstract | The present invention relates to the use of a polynucleotide comprising a sequence of formula (I): - TGACCTNOGGGCT-, in which N represents any natural or synthetic nucleotide base and O represents an A, T or U base, in wherein said sequence of formula (I) or complementary to (I) allows the selective interaction of said polynucleotide with one or more constituent elements of the PPARalpha transcription complex. This use makes it possible to evaluate the transcriptional activity of PPAR, to identify new PPARalpha specific ligands and sequence, as well as to diagnose and treat diseases related to PPAR activity dysregulation. The invention furthermore relates to a vector comprising a polynucleotide as defined above, a cell transformed with this vector, as well as kits for characterizing the activity of PPAR comprising such a polynucleotide. |
| priorityDate | 2004-12-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 443.