http://rdf.ncbi.nlm.nih.gov/pubchem/patent/FR-2865736-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b84a3b6a4ca4ad93b43df63be5bd6f26 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-01 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4703 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 |
| filingDate | 2004-06-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8515b159aecd203f94d0cca0e48efc79 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_49f9e62748f3e9c54255ce357ea41c08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e2e37dd99e367326fd10b37f4e2cc124 |
| publicationDate | 2005-08-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | FR-2865736-A1 |
| titleOfInvention | INHIBITORS OF ANGIOGENESIS, COMPOSITIONS CONTAINING SAME AND USE THEREOF FOR THE TREATMENT OF DISEASES ASSOCIATED WITH DEREGULATION OF ANGIOGENESIS |
| abstract | The present invention relates to a peptide molecule capable of interfering with the HLH domain of TAL-1, consisting of or comprising at least 10 successive amino acids and, preferably, at least 15 successive amino acids of the sequence HLH domain of TAL-1. : QQNVNGAFAELRKLIPTHPPDKKLSKNEILRLAMKYINFLA corresponding to SEQ ID No. 1 in the appended sequence listing or an equivalent sequence, said molecule being advantageously associated with a vector. The present invention also relates to a pharmaceutical composition containing said peptide molecule and the use of a compound capable of interacting with the HLH domain of TAL-1 for the preparation of a medicament for the prevention and / or treatment of diseases. related to angiogenesis and, preferably, to the treatment of cancers, arteriosclerosis and diabetes. Finally, the present invention also relates to a method for identifying a biologically active compound that can be used in the prevention and / or treatment of diseases related to angiogenesis and, preferably, the treatment of cancers, arteriosclerosis and of diabetes detecting the inhibition of the interaction between the HLH domain of TAL-1 and its partner E47 in the presence of said compound. |
| priorityDate | 2004-02-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 110.