abstract |
A compound capable of binding to interferon-gamma (IFN λ) chosen from the molecules corresponding to the following formula (I): in which X is a divalent spacer group of sufficient length to allow the two oligosaccharide fragments A and B each of them binds to one of the peptide sequences 125 to 143 of the C-terminal ends of an interferon λ (IFNλ) homodimer and n represents an integer from 0 to 10, for example equal to 0, 1, 2, 3, 4 or 5 and each R independently represents a hydrogen atom or an SO 3 - group, or phosphate, provided that no SO 3 - group is in position 3 of the glucosamine units of the compound (I). also the process for preparing these compounds, the complexes formed by these compounds and interferon-gamma, and the drugs comprising these compounds or complexes. |