| abstract |
The invention relates to the use of CD14 + monocytes for producing denditric cells.Use of CD14 + monocytes isolated from peripheral circulating blood for obtaining by differentiation of at least one mixed population of Langerhans cells and preconditioned interstitial dendritic cells undifferentiated, and / or differentiated and immature, and / or mature, and / or interdigitated. The invention includes their use in cellular and / or tissue models, in suspension, in monolayers and in three dimensions. The invention comprises the use of these models as study models, for the development of cosmetic and pharmaceutical active ingredients as well as for the development and implementation of cell and tissue therapy methods. |