| abstract |
The invention relates to triazolo [4,3-a] pyrido [2,3-d] pyrimidine-5-ones derivatives, their regioisomers, their salts and solvates if any, their preparation, the compositions containing them. and their use. These derivatives possess PDE4 inhibitory properties and / or TNFα release, and can therefore be used for the treatment or prevention of numerous conditions by inhibition of the PDE4 enzyme and the resulting increase in the level of cAMP. |