| abstract |
Compounds of formula (I): (CF DRAWING IN BOPI) in which:. X and Y represent a group chosen from hydrogen, halogen, mercapto, cyano, nitro, alkyl, trihaloalkyl, trihaloalkylcarbonylamino, ORa, NRaRb, -NRa-C (O) -T1, -OC (O) -T1, -O-T2 -NRaRb, -O-T2 -ORa, -NRa-T2 -NRaRb, -NRa-T2 -ORa, and -NRa-T2 -CO2 Ra in which Ra, Rb, T1, T2 are as defined in the description, or X and Y together form a methylenedioxy or ethylenedioxy group. R1 represents a hydrogen atom or an alkyl group ,. R2 represents a group selected from hydrogen, ORa, NRaRb, -NRa-C (O) -T1, -O-C (O) -T1; -O-T2 -NRaRb, -O-T2 -ORa, -NRa-T2 -NRaRb, -NRa-T2 -ORa, and -NRa-T2 -CO2 Ra in which Ra, Rb, T1 and T2 are as defined above ,. R3 and R4 represent a hydrogen atom or an alkyl group ,. W represents a group of formula -CH (R5) -CH (R6) -, -CH = C (R7) -, -C (R7) = CH-or -C (O) -CH (R8) - in which R5 , R6, R7 and R8 are as defined in the description, their isomers, N-oxides, as well as their addition salts with an acid or with a pharmaceutically acceptable base. Medicines. |