| abstract |
The present invention relates to a new 116 kDa polypeptide having sequence homologies with RNA helicases (DEXH box) called RH 116 and its fragments, the cloning of cDNA and the polynucleotides encoding said polypeptides, cloning vectors and / or expression including said polynucleotides, cells transformed by said vectors and specific antibodies directed against said polypeptides. The invention also relates to methods of detecting and / or assaying said polypeptides and polynucleotides, the corresponding diagnostic kits, and a method of screening for ligands, as well as compounds which can be used as medicaments for the prevention and / or treatment. therapeutic. |