| abstract |
The present invention relates to new heterocyclic derivatives exhibiting an inhibitory activity of calpains and / or a trapping activity of the reactive forms of oxygen, of formula (CF DRAWING IN BOPI) in which A, X, Y, R1, R2 and Het represent variable groups. The invention also relates to their preparation methods, the pharmaceutical preparations containing them and their use for therapeutic purposes, in particular as inhibitors of calpains and scavengers of reactive forms of oxygen, selectively or not. |