http://rdf.ncbi.nlm.nih.gov/pubchem/patent/FR-2788276-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_880cc8535f892eca8121f608c316808c |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-06139 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D237-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-078 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 |
| filingDate | 1999-01-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_24999c5693a777c3d5278f72c2ab5234 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6f7e74eb2ee6e673a7cd3f0585acf5ab |
| publicationDate | 2000-07-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | FR-2788276-A1 |
| titleOfInvention | NOVEL PROCESS FOR THE PREPARATION OF BICYCLIC COMPOUNDS AND THE APPLICATION OF THIS PROCESS AS AN INTERMEDIATE STEP FOR THE PREPARATION OF AN INTERLEUKIN 1-BETA (ice) CONVERSION ENZYME COMPOUND |
| abstract | The subject of the invention is a process for the preparation of compounds of formula (I) (CF DRAWING IN BOPI) in which R = H, alkyl, aryl or aralkyl containing up to 18 carbon atoms and the amine function can be free or protected, from a compound of formula (IA) (CF DRAWING IN BOPI) characterized in that the cyclization is carried out in a basic medium and in the presence of a phosphonic acid derivative in particular POCl3 or POBr3 and the use of this process as an intermediate step for the preparation of an interleukin 1-beta converting enzyme (ICE) inhibitor compound. |
| priorityDate | 1999-01-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 105.