| abstract |
The subject of the present invention is an improved multiparticulate tablet which disintegrates in the mouth on contact with saliva in less than 40 seconds, characterized in that it is based on particles of coated active principle, said particles having intrinsic characteristics of compression and of a mixture of excipients, the proportion of mixture of excipients with respect to the particles of coated active principle being from 0.4 to 6 parts by weight, the mixture of excipients comprising- a disintegrating agent- a soluble agent diluent with binding properties, - a lubricant, - a permeabilizing agent, and - advantageously lubricants, sweeteners, flavors and colors, the proportion of disintegrating agent and soluble agent relative to the mass of the tablet being 1 to 15% by weight for the first and 30 to 90% by weight for the second. |