http://rdf.ncbi.nlm.nih.gov/pubchem/patent/FR-2762843-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_37555e87c88017b74fba94c8b8abbb42 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-645 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-18 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-04 |
| filingDate | 1997-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e6cefac5680990e426d65b0db8d3535b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eb7dbc3d992e3a8f8f5b5d3b4f3d48e3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d30d28198302d7007bd611698f00a5eb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9734d4124c43228b68fb7766c19af61d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_79857de32c2c19b2a656449122ee7b61 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c973c10927e0e7b4e4a1931f291e8635 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4e0bdd98f20033b1deddb08010dcb1f0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_40c5b8fda11a3cc0b957169a80ac9a9e |
| publicationDate | 1998-11-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | FR-2762843-A1 |
| titleOfInvention | NOVEL CYCLOSPORIN DERIVATIVES, THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM |
| abstract | Cyclosporin derivatives of general formula (I) in which R is a hydrogen atom or a radical of structure (1a) for which Alk is a straight or branched (2 to 6C) alkylene or cycloalkylene (3 to 6C) radical and Rdegre is either H, OH, COOH or alkyloxycarbonyl, or a -NR1 R2 radical for which identical or different R1 and R2 represent H, alkyl, cycloalkyl (3 to 6C), phenyl optionally substituted (by an alkyloxy halogen atom, alkyloxycarbonyl, amino, alkylamino or dialkylamino), or represent benzyl or saturated or unsaturated heterocyclyl containing 5 or 6 members and 1 to 3 heteroatoms, or for which R1 and R2 form with the nitrogen atom to which they are attached a 5-membered heterocycle or 6 membered which may contain another heteroatom chosen from nitrogen, oxygen or sulfur and optionally substituted by alkyl, or a radical (1b) for which R1 and R2 are defined as above, R3 represents H or alkyl and n is an integer from 2 to 4; R' represents a radical (1c) or (1d) for which R4 is alkylthio, aminoalkylthio. alkylaminoalkylthio, dialkoylamino-alkylthio, pyrimidinylthio, thiazolylthio, N-alkylimidazolylthio, hydroxyalkylphenylthio, hydroxyalcolylphenyloxy, nitrophenylamino, 2-oxopyrimidin-1-yl, and R'4 represents alkyl; and R" represents H or OH, provided that R and R " are not simultaneously a hydrogen atom, the above alkyl portions or radicals being straight or branched and containing 1 to 4C, as well as their pharmaceutically acceptable salts when They exist. These new products are particularly useful for the treatment and/or prophylaxis of retrovirus infections. (CF DRAWING IN BOPI) |
| priorityDate | 1997-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 128.