abstract |
Diazepino-indolones of formula (I) (CF DRAWING IN BOPI) in which: - A is hydrogen, lower alkyl, nitro or amino; - B is hydrogen, optionally substituted lower alkyl; - Z is CH or N; - X1 and X2 , similar or different, may be hydrogen, halogen, lower alkyl, lower alkoxy, or alternatively -CH2 OH or -CO2 H optionally substituted; their racemic forms, their enantiomers, and their pharmaceutically acceptable salts, which are phosphodiesterase IV inhibitors. |