Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_47faba8c9a8306c182e3c7eb7d624118 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6827 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6832 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H21-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6832 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6827 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 |
filingDate |
1996-06-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c1d203341e1e16a9396b76f96e5a071c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_debef8583e063c7a6822bfa092d6d30c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1f5aa96bf95411120fd7e879c3f46189 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b2bacc79b638400e13d0bbb5dd193295 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0de83bad872d0845c98dafce579402b6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d7a7a10be4a26fde07c606cda44cd480 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fc5e1df4cd97e49eb51667b1b517c5a9 |
publicationDate |
1998-01-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
FR-2750435-A1 |
titleOfInvention |
METHOD OF FORMING HYBRIDIZATION COMPLEXES WITH STABILITY DEPENDS LITTLE OF THE COMPOSITION BASED ON TWO HYBRID NUCLEIC ACID MOLECULES |
abstract |
The present invention relates to a method of forming a hybridization complex whose stability depends little on the base composition of the two hybridized nucleic acid molecules, comprising contacting a first molecule of nucleic acid with a second molecule nucleic acid under conditions allowing the formation of a specific hybridization complex, characterized in that at least one of the four basic types entering the sequence of the first and / or second acid molecule nucleic acid is a modified base having pairing properties close to those of the natural base it replaces, so that at least one of the two types of base pair involved in the composition of the complex comprises a modified base and in that the set of base pairs used in the composition of said complex has a similar stability. |
priorityDate |
1996-06-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |