| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4d5a5ae085853db5173d99daca7b6669 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2123-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D451-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-0448 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D451-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-04 |
| filingDate |
1996-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2acc30ab093e0f449260447a8da455fb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_01f4a45de34251827624003f24db1de3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_20e17cafba496b54f6686ca298b21330
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d5a6b468d98cc1544f6b5ca0a4f1ccf4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_26cbc1c532d77018077aab876b6843b1 |
| publicationDate |
1997-11-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
FR-2748475-A1 |
| titleOfInvention |
TROPANE DERIVATIVES USED IN PARTICULAR FOR THE IN VIVO DETECTION OF DOPAMINE CARRIERS |
| abstract |
The invention relates to tropane derivatives which can be used in particular for the in vivo detection of dopamine transporters. These derivatives correspond to the formula: (CF DRAWING IN BOPI) in which R ** 1 is I or Sn (R ** 3) 3, R ** 2 is for example the methyl group, and X and Y are various substituents. The derivatives with X = CH3 and Y = H have a high specificity for the dopamine transporter compared to that of serotonin (74% inhibition when the transporter is saturated beforehand with GBR 12909). |
| priorityDate |
1996-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |