| abstract |
The invention relates to a new compound, useful for obtaining an anti-inflammatory and anti-rheumatic drug, of general formula: (CF DRAWING IN BOPI) in which R1 can be hydrogen, an acyl or an acyl substituted; R2 is hydrogen, lower alkyl, substituted lower alkyl, nitro, halogen, methylenedioxy, trifluoromethyl or OR '; Y is oxygen, sulfur or NR "; R3 is hydrogen, lower alkyl, substituted lower alkyl, phenyl, substituted aryl group, or a metal selected from the group consisting of sodium, potassium , calcium, magnesium, zinc and aluminum; R 'and R "are hydrogen, lower alkyl, substituted lower alkyl, phenyl or substituted aryl, and (a) in the group C1 - C2 substituted alkyl, at least one of the hydrogen atoms is replaced by lower alkyl, substituted lower alkyl, phenyl or substituted aryl; (b) in the substituted aryl group, at least one of the hydrogen atoms is replaced by lower alkyl, halogen, nitro, trifluoromethyl or OR '; (c) in the substituted acyl group, at least one of the hydrogen atoms is replaced by lower alkyl, substituted lower alkyl, phenyl or substituted aryl. |