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filingDate 1995-04-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_49031fecaae95f242e3fa800955b09d3
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publicationDate 1996-10-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber FR-2732605-A1
titleOfInvention COMPOSITION FOR INDUCING MUCOSAL IMMUNE RESPONSE
abstract The subject of the invention is a pharmaceutical composition intended to induce in a host mammal, a protective immune response against an antigen, at the level of an effector mucosal site, which comprises at least two identical or different products each containing an agent inducing the immune response selected from the antigen and provided that the antigen is of a protein nature, an expression cassette capable of expressing the antigen, for concomitant or consecutive administration; one of the products being formulated so as to be administered via the nasal-oral route so that the inducing agent is targeted towards the site (s) inducing an immune response at the level of the nasopharynx or salivary glands, the other product being formulated to be administered via an appropriate mucosal route other than the nasal route so that the inducing agent is targeted towards the site (s) inducing an immune response to level of the effector site where the immune response is sought. Optionally, such a composition can also comprise a third product, identical or different to the first two, formulated to be administered systemically.
priorityDate 1995-04-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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