http://rdf.ncbi.nlm.nih.gov/pubchem/patent/FR-2729390-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_37555e87c88017b74fba94c8b8abbb42 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C323-59 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C323-25 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-195 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C235-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-22 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-215 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-195 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C323-59 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C323-25 |
| filingDate | 1995-01-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ed5049420083c9dc6fbf84d90975d9ce http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bbc8f08892cf51481d68ffc9d702cd6e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_abcacda5cd34ad78a879ee6db32c2a4d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a1f9d2204ad5418698cb272822df522a |
| publicationDate | 1996-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | FR-2729390-A1 |
| titleOfInvention | NOVEL FARNESYL TRANSFERASE INHIBITORS, THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM |
| abstract | New farnesyl transferase inhibitors of general formula (I), their preparation and the pharmaceutical compositions which contain them. (CF DRAWING IN BOPI) In the general formula (I), R1 represents YS-A1 - (Y = hydrogen atom, amino acid residue, fatty acid residue, alkyl or alkoxycarbonyl radical, and A1 = alkylene radical containing 1 to 4 carbon atoms optionally substituted in alpha of the group> C (X1) (Y1) by an amino, alkylamino, alkanoylamino, alkoxycarbonylamino radical in which the alkyl or alkanoyl part contains 1 to 6 carbon atoms, X1 and Y1 each represent a hydrogen atom or together with the carbon atom to which they are attached form a group> C = O. R'1 represents hydrogen or an alkyl radical containing 1 to 6 carbon atoms, X represents an oxygen or carbon atom. sulfur, R2 represents an alkyl, alkenyl or alkynyl radical containing 1 to 6 carbon atoms optionally substituted by hydroxy, alkoxy, mercapto, alkylthio, alkylsulfinyl or alkylsulfonyl, it being understood that, when R2 represents an alkyl radical substituted by a hydroxy radical, R2 can train with the carboxy radical in alpha a lactone, R ′ 2 represents hydrogen or an alkyl radical containing 1 to 6 carbon atoms, and R represents a hydrogen atom or an optionally substituted alkyl radical or an optionally substituted phenyl radical. These new products exhibit anticancer properties. |
| priorityDate | 1995-01-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 28.