http://rdf.ncbi.nlm.nih.gov/pubchem/patent/FR-2728261-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5b65747ed78f05dd9ebe107b50ce2855 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D281-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D279-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D279-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D281-02 |
| filingDate | 1995-08-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_170542dc5d6d38edba7644b651e10569 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1f3e1ed292732d98b00bbf8c1751ec29 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b9f97e1f489e08f5a4ce649382fe3432 |
| publicationDate | 1996-06-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | FR-2728261-A1 |
| titleOfInvention | THIAZINE OR THIAZEPINE DERIVATIVES USEFUL AS INHIBITORS OF NO-SYNTHETASE |
| abstract | The subject of the invention is thiazine or thiazepine derivatives of the following general formula (I) or their pharmaceutically acceptable salts (CF DRAWING IN BOPI) in which R ** 1 is a hydrogen atom, a substituted alkyl group or not, a cycloalkyl group, a substituted or unsubstituted alkenyl group, a substituted or unsubstituted alkynyl group, a substituted or unsubstituted aryl group, a substituted or unsubstituted heteroaryl group, or a substituted or unsubstituted aralkyl group; R ** 2, R ** 3, R ** 4 and R ** 5, which may be the same or different, are each a hydrogen atom, a substituted or unsubstituted alkyl group, or R ** 1 taken together with R ** 2 or R ** 3 can represent - (CH2) n - where n is an integer from 1 to 6; A is an oxygen atom, a sulfur atom or an NH group; m is 0 or 1; and p is equal to 0 or 1. These compounds have an inhibitory activity of NO-synthetase and can be used in the treatment of conditions related to an excessive production of nitric oxide in vivo. |
| priorityDate | 1994-12-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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