| abstract |
The invention relates to the use of a recombinant vector containing in its structure at least one promoter and a nucleic acid sequence encoding a substance of interest of protein nature provided with a signal sequence, flanked at 3 'by a polyadenylation sequence, in the manufacture of a composition which, when brought into contact with kidney cells of animals, preferably mammals, induces the expression of said substance of interest in these cells and its production in the blood or urine of said animals, preferably mammals. |