| abstract |
Compounds corresponding to formula (I) (CF DRAWING IN BOPI) in which Ar represents an aryl group optionally substituted by one or more radicals chosen from chlorine and fluorine atoms and the methyl group, R1 represents a hydrogen atom, R2 represents either a straight or branched (C1 -C6) alkyl group, or a pyridin-4-yl group, or a piperidin-3-yl group substituted in position 1 by a (C1 -C4) alkoxycarbonyl group, or a piperidin group -4-yl substituted in position 1 by a (C1 -C4) alkoxycarbonyl group, or a piperidinyl (C1 -C6) alkyl group substituted in position 3 or 4 on the piperidine ring by a -COX group where X is a (C1) group -C4) alkoxy, amine, or hydroxy, (CF DRAWING IN BOPI) group (C1 -C4) alkoxy, and n = 0 or 1, in the form of cis or trans stereoisomers, and in the form of free bases or salts of addition to pharmaceutically acceptable acids. Application in therapy. |