| abstract |
The invention relates to nucleoside derivatives, methods of making these nucleoside derivatives, as well as polyclonal and monoclonal antibodies specific for the above derivatives. These derivatives correspond to the following chemical formula: (CF DRAWING IN BOPI) in which R1 represents H or a linear mono, di or tri-phosphoric acid, R2 represents a hydroxyl group, an alkyl group, an aryl group, a protein comprising a free amino site, an aminoalkyl polystyrene or a silica grafted with an alkylamine chain and R3 represents a substituted base chosen from uracil, thymine, cytosine, guanine or adenine. |