abstract |
A subject of the invention is methylguanidine derivatives, which can be used as medicaments, of general formula: (CF DRAWING IN BOPI) in which: The asterisk indicates an asymmetric carbon. R1, R2 and R3, identical or different, represent hydrogen, a halogen, a C1 -C4 alkyl, C1 -C4 alkoxy, phenyl or benzyl or R1, R2 and R3, taken together with the carbon atoms located in positions 5 and 6 form a C4 -C6 ring, R4 and R5, which are identical or different, represent: - hydrogen - a C1 -C1 2 alkyl group - a benzhydryl group - an optionally substituted aralkyl group - an alkyl group substituted of formula: (CF DRAWING IN BOPI) represents hydrogen or a C1 -C4 alkyl group and n represents 0 to 3, Cy represents an optionally substituted cyclic system, (CF DRAWING IN BOPI) |