| abstract |
The present invention relates to complex solid particles each composed of at least two solid substances, at least one of which is biologically active. The biologically active solid substance is composed of at least one biologically active product and is regularly distributed on the surface of a grain made up of the other solid substance forming a core, called a support substance, said grain having a dimension of between 0.05 and 100 mum (microns) and the weight ratio of said active substance to said core substance is between about 10-4 and 1.5. The invention also relates to a process for the preparation of these particles, a process for the treatment of. a biological surface to accelerate the bioavailability of a biologically active substance. It also relates to compositions for topical use containing the particles of the invention. |