| abstract |
New lupane derivatives of general formula (I) in which R is: (CF DRAWING IN BOPI) in which R ', R ", Rdegre and Rdegré degree identical or different are H or alkyl, X is a bond or carbamoyl, Y is a bond or p.phenylene and, n, m and p are integers from 0 to 16, 4 <= m + n + p <= 16, R1 is methyl, R2 is hydroxy, methyl, hydroxymethyl or amino substituted by hydroxyalkyl, carboxy, hydroxy, or alkyl, R3 is H or together with R1 or R2 form methylene or oxo, R4 and R5 are different and represent H or hydroxy, or together form oxo, hydroxyimino or alkyloxyimino which may be substituted, and R6 and R7 are H , or else R4 and R5, and R6 and R7 together form oxo radicals, the alkyl radicals (1 to 4C) being straight or branched, as well as their salts when they exist and their preparation. The new products according to the invention are particularly interesting in the field of AIDS. (CF DRAWING IN BOPI) |