| abstract |
The invention relates to the field of organic chemistry and more particularly to that of therapeutic chemistry. It relates more particularly to novel quaternary ammonium salts of general formula I (CF DRAWING IN BOPI) in which Hal is a halogen atom other than fluorine R and R1, identical or different, are lower alocyl radicals n is a integer varying from 2 to 16 Z is an alkenyl radical having up to 3 carbon atoms, a carboxyl or the OR2 group in which R2 is hydrogen, a lower alkyl radical, an acyl residue, a tocol radical, a sterolic radical or a carboxamide chain and A is a hydroxyl or the anion of a mineral or organic acid. The compounds according to the invention are the active principles of pharmaceutical compositions with anti-tumor and / or immunosuppressive action. |