| abstract |
The subject of the invention is the products of formula (I): in which: A represents the residue of a saturated or unsaturated carboxyclic or heterocyclic radical, R represents alkyl, alkenyl or alkynyl, R1, R2, R3 and R4, in particular represent hydrogen ; halogen; hydroxyl; cyano; nitro; sulfo; formyl; benzoyl; acyl; acyloxy; carboxy; mercapto; alkyl; alkenyl; alkynyl; alkoxy; alkylthio; aryl; arylalkyl; arylalkenyl; - (CH2) m -SO2 -X-R1 4; with m represents 0 to 4, and either X-R1 4 represents NH2 or X represents -NH-, -NH-CO-NH- or -NH-CO- or single bond and R1 4 represents alkyl, alkenyl or aryl R5 represents alkylene , Y represents -Y1 -B-Y2 in which: Y1 represents aryl optionally substituted by R1, R2, R3 and R4, B represents: either single bond between Y1 and Y2, or -CO-, -NH-CO-, -CO -NH- or -O- (CH2) n - with n represent 0 to 3, Y2 represents Y1, if B represents a single bond, hydrogen, cyano, carboxy, said products of formula (I) being in all the possible isomeric forms, as well as the addition salts of said products of formula (I), their application as medicaments and the pharmaceutical compositions containing them. (CF DRAWING IN BOPI) |