| abstract |
The present invention relates to a process for the preparation of benzene derivatives having two substituents in meta to each other and the intermediate compounds. This process comprises step a) reaction of a compound of formula (I) (CF DRAWING IN BOPI) in which Y represents a chalcogen, preferably an oxygen; or together the groups O-Y 'and R1. - where R1 can be a hydrogen, an alkyl, an alkoxyl or an aryl; - where Y 'can be hydrogen, alkyl or aryl; Y 'and R1 possibly together forming a cyclic group; R2 represents an alkyl, R4 represents a hydrogen, an alkyl or a fluorine; Si represents a reactive silyl group; with an electrophilic reagent. |