| abstract |
a) Method for demonstrating and analyzing the cellular degeneration following the oxidation induced by free radicals of polyunsaturated fatty acids of membrane phospholipids, oxidation releasing a dialdehyde reacting with the free primary amine functions of cellular proteins to give modified proteins of immunogenic nature, b) process characterized in that one reacts, with the dialdehyde, a predetermined sample peptide or polypeptide, the modified sample peptide or polypeptide thus obtained is injected into an experimental animal, so as to induce the formation of antipeptide or antipolypeptide antibody modified sample, then after obtaining these antibodies, they are brought into contact with the cells to be analyzed and the antigen-antibody complex thus obtained is demonstrated and analyzed. |