http://rdf.ncbi.nlm.nih.gov/pubchem/patent/FR-2650955-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_88fd9074e7f5629511f3a410b1316b5f |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4732 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 |
| filingDate | 1989-08-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_780ada8fe69cac84f5a7b525a9cd5c84 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8f880aa1199355c587689c64b3b1d237 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c6283406aaca8de1e74b46f1bae6ae60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_62449fb649d169907a0e834acca7602f |
| publicationDate | 1991-02-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | FR-2650955-A1 |
| titleOfInvention | METHOD FOR OBTAINING, FROM BETA CASEIN, FRACTIONS ENRICHED WITH PEPTIDES WITH BIOLOGICAL ACTIVITY AND THE PEPTIDE FRACTIONS OBTAINED |
| abstract | To obtain, from beta casein, a partial hydrolyzate enriched, on the one hand, in phosphopeptide or peptide fraction 1-25, and, on the other hand, in precursors of beta-casomorphin (these precursors being fragments covering zone 33-97 of the beta casein molecule), by hydrolysis of beta casein by a proteolytic enzyme, this hydrolysis is carried out in a saline medium, causing the appearance in the medium of a precipitate which is separated from the soluble phase, which constitutes the desired partial hydrolyzate. Preferably, this hydrolysis is carried out in a medium with an ionic strength equivalent to that of a solution of monovalent salt of between 0.5 and 4M. To obtain the peptide fraction 1-25 and the precursors of beta-casomorphin, ion exchange chromatography is carried out on this soluble phase, after having demineralized it by electrodialysis. To obtain the peptide fraction 177-183 with antihypertensive and immunostimulating activity, the precipitate obtained is resolubilized, the resulting solution is brought to a pH of 6-9, and hydrolysis is carried out by a proteolytic enzyme. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1206911-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2004002509-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2004002509-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1206911-A4 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1374885-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/FR-2841473-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0580694-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0580694-A4 |
| priorityDate | 1989-08-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 323.