| abstract |
THE PRESENT INVENTION RELATES TO COMPOUNDS OF FORMULA XXI: (CF DRAWING IN BOPI) AND THEIR ADDITIONAL SALTS OF PHARMACEUTICALLY ACCEPTABLE ACIDS ANDOR THEIR HYDRATES, IN WHICH: X REPRESENTS -C-, O - O, OR -CR -, R BEING CC UNALKYL, A HYDROGEN OR A FLUOROPHENYL; Y REPRESENTS HALOGEN OR HYDROGEN, PROVIDED THAT Y REPRESENTS ONLY A HALOGEN WHEN X REPRESENTS A CARBONYL AND Z IS A HYDROGEN; AND Z REPRESENTS A LOWER ALKOXY OR HYDROGEN. PHARMACOLOGICAL APPLICATION OF THESE DERIVATIVES IN PARTICULAR AS ANTIPSYCHOTICS. |