| abstract |
THE INVENTION CONCERNS A PROCESS FOR MANUFACTURING AMINO ACIDS WITH A PROTECTED AMINE FUNCTION BY REACTION IN A SOLVENT MEDIUM, AND THE PRESENCE OF AN ACID BINDING AGENT AND, AT A TEMPERATURE BETWEEN -5 AND 100C, A CARBONATE A. -HALOGEN OF FORMULA: (CF DRAWING IN BOPI) IN WHICH R AND R INDEPENDENTLY OR RELATED REPRESENT THE USUAL RADICALS OF NATURAL OR SYNTHETIC AMINO ACIDS. ON AMINO ACIDS THUS BLOCKED, ANY DESIRED COUPLING OPERATIONS FOR THE ACID FUNCTION NECESSARY IN PEPTIDIC SYNTHESIS CAN BE CARRIED OUT. |