| abstract |
COMPOUNDS OF DEVELOPED FORMULA: (CF DRAWING IN BOPI) IN WHICH R IS FOR EXAMPLE AN ARYULALKYL RADICAL, R AND R ARE EACH HYDROGEN ATOM OR LOWER ALKYL RADICAL, ARYLALKYL, BENZHYDRYL OR-CH-OCR OR R IS AN ATOM HYDROGEN OR UNRADICAL LOWER ALKYL OR PHENYL; N IS 0 OR 1; R IS FOR EXAMPLE A RADICAL OF THE FORMULA NH (CH) IN WHICH M IS AN INTEGER FROM 2 TO 5, AND X-OR IS AN IMINO-ACID OR AMINO-ACID DERIVATIVE. THESE COMPOUNDS ARE ANGIOTENSIN TRANSFORMATION ENZYME INHIBITORS AND THEREFORE CAN BE USED FOR THE TREATMENT OF HYPERTENSION. |