| abstract |
AZINO RIFAMYCIN COMPOUNDS, OF FORMULA I: (CF DRAWING IN BOPI) IN WHICH YH OR CHCO; R IS A LINEAR OR BRANCHED ALKYL C-C OR A C-C ALKENYL; R IS A LINEAR OR RAMIFIED ALKYL CC, A CHLOROALKYL CC, A ALKENYL CC, A CYCLOALKYL HAVING 3 TO 7 CARBON ATOMS IN THE RING, A CYCLOALKYL ALKYL HAVING 3 TO 6 CARBON ATOMS IN THE RING, A PHENYL PHENYL OR CC ARALKYL, NOT SUBSTITUTED OR MONO-SUBSTITUTED BY A HALOGEN ATOM IN THE ARYL GROUP, OR NRR IS A CYCLIC FRACTION HAVING 5 TO 8 CARBON ATOMS, NOT SUBSTITUTED OR SUBSTITUTED BY 1 OR 2 CH MORPHOLINO GROUPS. THESE COMPOUNDS INHIBIT THE GROWTH OF POSITIVE GRAM BACTERIA AND MYCOBACTERIUM TUBERCULOSIS. |