| abstract |
THE INVENTION CONCERNS A PROCESS FOR PREPARING DIALURIC ACIDS SUBSTITUTED IN POSITION 5. THE PROCESS CONSISTS OF REACTING THE ALLOXANE WITH AN ORGANOMETAL REAGENT CONTAINING LITHIUM OR MAGNESIUM, IN AN INERT SOLVENT AT A TEMPERATURE OF -90 TO 50C. DIALURIC ACIDS SUBSTITUTED IN POSITION 5 ARE USEFUL AS INTERMEDIATE COMPOUNDS FOR THE SYNTHESIS OF CERTAIN OXAZOLIDINE-2, 4-DIONES SUBSTITUTED IN POSITION 5, WITH HYPOGLYCEMIC ACTIVITY. |