| abstract |
NEW ANTIMICROBIAL COMPOUNDS. THE COMPOUNDS MEET THE ZBYBZ FORMULA IN WHICH B IS A CARBAMYLGUANIDINO OR A THIOCARBAMYLGUANIDINO AND IS AN ALKYLENE NITROGEN OF THE FORMULA: (CF DRAWING IN BOPI) IN WHICH: N 2-4, M 2-4, P 1,2, Q 2-4, X 0-3, Y 0-2; X 0 WHEN Y 0 AND Y 0 WHEN X 0; R IS HYDROGEN OR A C-C HYDROCARBON; R AND R ARE EACH HYDROGEN OR A CC ALKYL AND MAY BE THE SAME OR DIFFERENT; Z IS CHOSEN FROM THE GROUP INCLUDING AN ALKYL IN C-C; UN DI (ALKYLAMINO EN C-C) - (ALKYL EN C-C); A C-C ALCENYL; A CC ALCYNYL, A CC CYCLOALKYL, A CC CYCLOALKYLALKYL, A CC CYCLOALCENYL, A CC CYCLOALCENYLALKYL, A CC POLYCYCLOALKYL, A POLYCYCLOALKYLALKYL IN CC, A CC POLYCYCLOALKYLALKYL, A CC ) - (ALKYL IN CC); ONE (C-C ALKYLTHIO) - (C-C ALKYL); A PHENOXY (C-C ALKYL); A PHENYLTHIO- (C-C ALKYL); AN ARYLE IN C-C; A C-C ARALKYL AND AN ARYLCYCLOALKYL; A BENZOCYCLOALKYL IN C-C, AN ARYL IN C-C AND A SUBSTITUTE ARALKYL AS WELL AS THE PHARMACEUTICALLY ACCEPTABLE ACID ADDITION SALTS OF THESE COMPOUNDS. USE AGAINST THE MICRO-ORGANISMS WHICH PRODUCE THE DENTAL PLATE. |