| abstract |
GLUCOPYRANOSE-NITROSOUREE COMPOUNDS WITH ANTITUMOR ACTIVITY ARE REPRESENTED BY THE FOLLOWING GENERAL FORMULA: (CF DRAWING IN BOPI) OR R REPRESENTS A CHOSEN MEMBER IN THE GROUP CONSISTING OF AN ALKYL GROUP RAMIFIED, FROM GROUP 4 TO 9 CYCLOHEXYL, OF THE MONO (OR TRI) METHYLCYCLOHEXYL GROUP, OF THE BENZYL GROUP, OF THE METHYLPHENYL GROUP, OF THE PHENYLETHYL GROUP AND OF A NORMAL ALKYL GROUP HAVING 5 TO 10 CARBON ATOMS; THESE COMPOUNDS MAY BE PRODUCED BY REACTION OF CORRESPONDING AMINO-GLUCOPYRANOSE COMPOUNDS, HAVING AN AMINO GROUP OR AMINO GROUP ADDED TO AN ACID, WITH COMPOUNDS OF N- (2-CHLOROETHYL) -N-NITROSOCARBAMATE O- (OR OF P-) NITRO- OR OF O- (OR OF P-) CYANO-PHENYL. |