| abstract |
THE INVENTION RELATES TO COMPOUNDS HAVING ANTI-ULCEROGENIC ACTIVITY; THESE COMPOUNDS COMPLY WITH THE FOLLOWING FORMULA: (CF DRAWING IN BOPI) IN WHICH HET IS A PYRIDINYL GROUP POSSIBLY SUBSTITUTED; X IS A CN GROUP, TRIFLUOROMETHYL OR AN AMIDO GROUP OF FORMULA -C (A) NRR WITH AO OR S, R IS H OR AN ALKYL GROUP, R IS AN H OR AN ALKYL GROUP, OR R AND R FORM TOGETHER WITH THE NITROGEN ATOM A HETEROCYCLE IN WHICH ANOTHER HETERO-ATOM MAY BE PRESENT; AND R IS AN ALKYL, CYCLOALKYL, CYCLOALKYLALKYL, ALCENYL, ALCYNYL, PHENYLALKYL GROUP, POSSIBLY SUBSTITUTED BY A HALOGENO, ALCOXY, NITRO, CYANO OR TRIFLUOROMETALKYL GROUP - OR A CHANNEL OF CHANO OR TRIFLUOROMETALKYL 2 - M1 OR 2 (M1) OF CHANNEL 2 - NR-M1 OCHYB (M1) OR 2NC-OLYROMETHYL - M1 , R IS H OR AN ALKYL GROUP, R IS H OR AN ALKYL GROUP, OR R AND R FORM TOGETHER WITH THE NITROGEN ATOM A HETEROCYCLE, OR A CYANOALKYL GROUP. THE INVENTION ALSO CONCERNS PHARMACEUTICAL COMPOSITIONS CONTAINING SAID COMPOUNDS. APPLICATION TO THE TREATMENT OF STOMACH ULCERS. |