abstract |
The present invention relates to a new process for preparing the nebramycin complex. This method is characterized in that a strain of Streptomyces tenebrarius is cultivated in a culture medium which contains nebramycin-2 and / or nebramycin-5 'and / or nebramycin-6, in that isolating the individuals which form aerial mycelium and spores and cultivating the new resistant strains thus obtained in a culture medium and at suitable temperatures. Application to the preparation of the nebramycin complex by microbiological route. |