http://rdf.ncbi.nlm.nih.gov/pubchem/patent/FR-2419278-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5120915c2421e046257f18b7035d6bf3 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-042 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-0808 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-083 |
filingDate | 1978-03-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_24bafac7c292e88abda14e8dd974c9b9 |
publicationDate | 1979-10-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | FR-2419278-A1 |
titleOfInvention | PEPTIDIC STRING SYNTHESIS PROCESS |
abstract | The invention relates to an improved method of synthesizing a peptide chain. An amino acid precursor complex containing a blocked alpha-amino or carboxy group and a carrier polynucleotide is reacted in aqueous solution with a second amino acid segment; the reacted complex is separated from the unreacted acid by reversibly coupling the polynucleotide of the complex to a complementary adsorbent polynucleotide immobilized on an insoluble support and the complex is eluted from the support as an aqueous solution. enzymatically the complex and used as a precursor to repeat the reaction with another acid, and so on until the precursor has been set the desired number of acids. Preferably, during the process, the chains which have not reacted with a given acid are removed by enzymatic degradation. This process makes it possible to safely obtain peptide chains of high molecular weight which actually correspond to the desired peptide chain. |
priorityDate | 1978-03-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 16.