| abstract |
THESE OPTICALLY ACTIVE BASES ARE OBTAINED BY MEANS OF DICARBOXYLIC ACIDS AMIDES. THE RACEMIC BASES ARE REACTED WITH AN OPTICALLY ACTIVE AMID ACID OF AN ALIPHATIC DICARBOXYLIC ACID UNSATURATED OF GENERAL FORMULA I BELOW AND WE DECOMPOSE, IF NECESSARY AFTER FRACTIONING, AT LEAST ONE OPTICALLY HOMOGENEOUS SALT FRACTION AND CORRECTLY ACTIVE IN THE BASE OPTICALLY HOMOGENEOUSLY ACTIVE IN THE BASE IN THE STARTING ACID AMID. THIS PROCESS ALLOWS SIMPLY AND WITH THE NECESSARY PURITY TO OBTAIN OPTICALLY ACTIVE AMINES WITH PHYSIOLOGICAL ACTIVITY. (CF DRAWING IN BOPI) R, R, R, SIMILAR OR DIFFERENT, H, HAL, OH, CH, CHOH OR TWO OF THESE RADICALS TOGETHER REPRESENT A METHYLENE-DIOXY, RH OR CH GROUP, THE R, R AND R RADICALS REPRESENT , INDEPENDENT OF ONE OF THE OTHERS, OF HYDROGEN ATOMS OR 1-4C ALCOHOL GROUPS; N0.1. |