http://rdf.ncbi.nlm.nih.gov/pubchem/patent/FR-2403345-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2ca2e4410855da087e11bf3eea8933fa |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-36 |
classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-545 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K- http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D- http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-00 |
filingDate | 1978-09-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_acb377bcb7067ebf730e194d0c8a20f3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cbe51e2af65d6b140f1a5350be0264fa |
publicationDate | 1979-04-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | FR-2403345-A1 |
titleOfInvention | PROCESS FOR OBTAINING PURE 7- (D-MANDELAMIDO) -3- (1-METHYL-1,2,3,4-TETRAZOL-5-YL) THIOMETHYL-3-CEPHEM-4-CARBOXYLIC ACID FROM ITS SALTS |
abstract | The invention relates to a process for the preparation of pure cefamandole from its alkali metal and ammonium salts. A solution, buffered at a pH of about 3.5 to about 4.5, of an alkali metal or ammonium salt of cefamandole is passed through a bed of an adsorbent resin which uses adsorbent for adsorption. van der Waals forces, then the eluate is acidified to a pH of about 2.0 with a non-oxidizing mineral acid and pure cefamandole crystals are obtained which can be separated and dried and which are can transform into crystalline cefamandole sodium, a form which is very useful for preparing pharmaceutical compositions. |
priorityDate | 1977-09-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 22.