abstract |
The invention relates to novel chemical compounds. Carbohydrate derivatives of the antibiotic substance milbemycin, also called B-41, and 13-hydroxy milbemycin are prepared. Carbohydrate groups are attached to the hydroxy groups introduced synthetically at position 13. Reactions can be carried out selectively so that more than one carbohydrate group can be attached at a same position or more carbohydrate groups multiple can be attached to different positions on the molecule. The described carbohydrate derivatives have antiparasitic activity. |