| abstract |
New 3-Ø4 (2'-pyridyl) -pyperazin-1-ylõ- (3,4,5-trimethoxybenzoyloxy) -propane and its acid addition salts. The preparation of these compounds consists in reacting 3-Ø4- (2'-pyridyl) -piperazin-1-ylõ-hydroxy-propane with 3,4,5-trimethoxybenzoic acid or with a derivative thereof capable of acylation or reacting 4- (2'-pyridyl) -piperazine with a 1- (3,4,5-trimethoxy-benzoyloxy) -3-halogeno-propane and optionally converting the product obtained into a salt of acid addition. Application of the new compound and its physiologically acceptable acid addition salts as strong antiarrhythmic drugs. |