| abstract |
The antibiotic mixture A-35512 containing the factors A, B, C, E, F, G and H, antibiotic A-35512 factor A, antibiotic A-35512 factor B, antibiotic A-35512 factor C, antibiotic A-35512 factor E, antibiotic A-35512 factor F, antibiotic A-35512 factor G and antibiotic A-35512 factor H and also antibiotic A-35512 factor B aglycone are prepared. This antibiotic mixture and these factors are obtained by submerse culture under aerobic fermentation conditions of the microorganism Streptomyces candidus NRRL 8156 in a nutrient medium which contains assimilable sources of carbohydrates, nitrogen and inorganic salts until a substantial amount of the antibiotic is formed. The antibiotics obtained can be used as antibacterial agents and as growth-promoting agents for increasing the feed utilisation in ruminants and poultry. |